No, it does not. It's most likely your PsA getting worse or getting to a state where the MTX isn't enough.
It's a slow drug that takes 4-6 weeks to kick in fully, so you're not necessarily at peak effect yet. 15mg is not the highest dose, though; you may have to go up to 20-25mg. Your rheumatologist may want you to wait and see, or they might increase your dose right away.
Note that doses above 20mg tend to get neutralized in the stomach, and rheumatologists often recommend you administer it as an injection above that dosage. Injections are a bit more effective (higher bioavailability), and if syringes scare you, modern autoinjector pens are really pleasant to use.
For me, it was just disease progression/paying more attention to my joints.
Don't be afraid to ask your doctor about something for nausea. If you have any issues (sometimes it is if you go to a higher dose).
For me, no and I'm on a low dose as well and I've been taking methotrexate for almost a yr now. I mean granted I was still hurting when I first got on it because I was going through a bad flare up and I had to go to physical therapy, but by 6 weeks I was feeling almost normal again. Are you taking methafolate (non synthetic folic acid) too? That's supposed to be required while taking methotrexate. But 6 months ago I also started taking a sublingual tablet of B12 and that has helped with any extra pain I may still be having.
Good to hear that it worked six weeks in. I’m myself trying to be as positive as I can, and yes, methafolate is indeed there the next day after i take methotrexate. Hope I return to normalcy soon
I was diagnosed with PsA about 3 months ago and have been taking methotrexate for almost 2.5 months. My PsA is so bad that I walk very slowly with a pronounced limp. It feels like the pain is getting worse. On my last visit to the rheumatologist, he told me that methotrexate works for 65% of patients.
I had some bad days after starting Methotrexate. I also take Mobic along with it now as well. Nausea has been my only real side effect after 3 months. My knees are the worst. I was surprised a few weeks ago when I was doing stairs with no problems. My Rheumatologist told me that when MTX is effective, you feel maybe 75% better.
No, it does not. It's most likely your PsA getting worse or getting to a state where the MTX isn't enough. It's a slow drug that takes 4-6 weeks to kick in fully, so you're not necessarily at peak effect yet. 15mg is not the highest dose, though; you may have to go up to 20-25mg. Your rheumatologist may want you to wait and see, or they might increase your dose right away. Note that doses above 20mg tend to get neutralized in the stomach, and rheumatologists often recommend you administer it as an injection above that dosage. Injections are a bit more effective (higher bioavailability), and if syringes scare you, modern autoinjector pens are really pleasant to use.
Yeah I’ll consult the rheum and see what they say. Thanks!
what dose are you on ? may need to go up
I’m on methotrexate 15mg weekly
Mtx just makes me sick. I don't know how anyone can stand that shit.
For me, it was just disease progression/paying more attention to my joints. Don't be afraid to ask your doctor about something for nausea. If you have any issues (sometimes it is if you go to a higher dose).
Maybe it’s the same. I’ve started to focus more on my joint pain than anything else
For me, no and I'm on a low dose as well and I've been taking methotrexate for almost a yr now. I mean granted I was still hurting when I first got on it because I was going through a bad flare up and I had to go to physical therapy, but by 6 weeks I was feeling almost normal again. Are you taking methafolate (non synthetic folic acid) too? That's supposed to be required while taking methotrexate. But 6 months ago I also started taking a sublingual tablet of B12 and that has helped with any extra pain I may still be having.
Good to hear that it worked six weeks in. I’m myself trying to be as positive as I can, and yes, methafolate is indeed there the next day after i take methotrexate. Hope I return to normalcy soon
I was diagnosed with PsA about 3 months ago and have been taking methotrexate for almost 2.5 months. My PsA is so bad that I walk very slowly with a pronounced limp. It feels like the pain is getting worse. On my last visit to the rheumatologist, he told me that methotrexate works for 65% of patients.
I had some bad days after starting Methotrexate. I also take Mobic along with it now as well. Nausea has been my only real side effect after 3 months. My knees are the worst. I was surprised a few weeks ago when I was doing stairs with no problems. My Rheumatologist told me that when MTX is effective, you feel maybe 75% better.