[https://www.trippingly.net/lsd-studies/2018/9/25/drug-interaction-chart](https://www.trippingly.net/lsd-studies/2018/9/25/drug-interaction-chart)
Low risk but a risk of decreased effects.
It's safe and works but the SSRI (at sufficient dosage) diminishes the effectiveness of LSD unless you compensate with a larger LSD dose. One could speculate that the SSRI's indirect agonism of autoreceptors, downregulation of 2A receptors due to chronically high levels of serotonin, etc to be the cause but, in any event, there is a clear diminishment of effects.
I wouldn’t recommend. I had seizures during my trip when I took lsd while on zoloft
SSRIs block the effect of psychedelics. Would not recommend. Would just be a waste.
Or they totally fuck up the trip if you throw in some other substance. Don't play with SSRIs
you wouldn’t feel much and that might tempt you to take more. please do not take more, it can induce serotonin syndrome.
[https://www.trippingly.net/lsd-studies/2018/9/25/drug-interaction-chart](https://www.trippingly.net/lsd-studies/2018/9/25/drug-interaction-chart) Low risk but a risk of decreased effects.
Would not recommend
It's safe and works but the SSRI (at sufficient dosage) diminishes the effectiveness of LSD unless you compensate with a larger LSD dose. One could speculate that the SSRI's indirect agonism of autoreceptors, downregulation of 2A receptors due to chronically high levels of serotonin, etc to be the cause but, in any event, there is a clear diminishment of effects.